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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NIPBL
All Species:
20
Human Site:
S1134
Identified Species:
48.89
UniProt:
Q6KC79
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KC79
NP_056199.2
2804
316051
S1134
D
H
R
R
S
G
H
S
H
E
G
R
R
S
S
Chimpanzee
Pan troglodytes
XP_001146002
2804
316033
S1134
D
H
R
R
S
G
H
S
H
E
G
R
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001096462
2804
316103
S1134
D
H
R
R
S
G
H
S
H
E
G
R
R
S
S
Dog
Lupus familis
XP_546344
2804
316124
S1134
D
H
R
R
S
G
H
S
H
E
G
R
R
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6KCD5
2798
315432
S1128
D
H
R
R
S
G
H
S
H
D
G
R
R
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509151
2821
317768
G1149
S
G
D
H
R
R
S
G
H
S
H
E
G
R
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001154919
2856
323576
S1155
D
H
R
R
S
F
D
S
R
R
S
S
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI2
2077
236710
K489
L
S
N
T
K
C
V
K
E
E
V
T
R
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95XZ5
2203
252800
F615
E
E
D
V
Q
H
F
F
G
S
Q
K
K
R
R
Sea Urchin
Strong. purpuratus
XP_793995
2228
251283
F639
E
L
M
D
T
P
T
F
K
R
F
N
A
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.2
98
N.A.
96.6
N.A.
N.A.
91.8
N.A.
N.A.
68.6
N.A.
26.6
N.A.
25.1
37.9
Protein Similarity:
100
100
99.7
99.1
N.A.
98.7
N.A.
N.A.
95.8
N.A.
N.A.
80.8
N.A.
44.4
N.A.
43.4
54.6
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
40
N.A.
20
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
40
N.A.
20
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
20
10
0
0
10
0
0
10
0
0
0
0
0
% D
% Glu:
20
10
0
0
0
0
0
0
10
50
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
20
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
50
0
10
10
0
50
0
20
10
0
% G
% His:
0
60
0
10
0
10
50
0
60
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
10
10
0
0
10
10
0
0
% K
% Leu:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
0
60
60
10
10
0
0
10
20
0
50
60
20
30
% R
% Ser:
10
10
0
0
60
0
10
60
0
20
10
10
0
60
50
% S
% Thr:
0
0
0
10
10
0
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _